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Ibumix
  • Technology
    • Bioavailability
    • The tablet problem
    • Lipid & liquid-crystal delivery
    • GRAS & established materials
    • TECHNOLOGY – The Ibumix™ Platform
    • Science and data
    • The Structural Problem Behind Poor Drug Solubility
    • Products
    • Drug-delivery and formulation glossary
  • Company
    • About Ibumix
    • Investor overview
    • Newsroom
    • Connect
  • Insights
9 October 202611 October 2026TechnologyBy George Forrest

The Footprint Is in the Molecule

Pharma’s sustainability problem was never a factory problem. Four-fifths of the footprint sits in the supply chain and in the molecule itself. What changed in the last twelve months, who is now asking for what, and what a small developer should do about it.

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9 October 20269 October 2026TechnologyBy George Forrest

Hardest to Describe as Inactive

What 185 formulation professionals expect the excipient of 2030 to look like, and why it answers the question an IPEC-Europe panel put at CPHI Milan.

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13 September 202614 September 2026TechnologyBy George Forrest

It Isn’t Low. It’s Unstable.

The one per cent gets quoted. The variance around it is larger, less discussed, and a harder problem than the mean.

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13 September 202611 October 2026TechnologyBy George Forrest

Soluble and Impermeable

Why an oral peptide delivers about one per cent of its dose – and what the tablet has to carry to manage even that.

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6 September 20266 September 2026TechnologyBy George Forrest

The Molecule Must Earn the Patch

Five NSAIDs from one pharmacological class have five different transdermal fates. No molecular descriptor predicts which, and neither does the flux calculation that comes closest.

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Two Roads to One Pill: Novo Nordisk's oral semaglutide tolerates the bioavailability ceiling with SNAC, while Eli Lilly's Foundayo (orforglipron) avoids it as a small molecule
12 August 202617 August 2026TechnologyBy George Forrest

Two Roads to One Pill

Ozempic is a pill now, but oral bioavailability wasn’t solved. How Novo Nordisk and Eli Lilly reached comparable results by two opposite routes.

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10 August 202612 August 2026TechnologyBy George Forrest

The Third Battle, Better on Paper

A 2020 mouse study hit an oral bioavailability no approved oral peptide drug has matched in a human. Why lipid-based delivery — […]

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A dark navy chair sits beside a vertical curtain of falling gold data particles, separated by a thin dividing line — representing proximity to data without access to it.
3 August 202627 August 2026TechnologyBy George Forrest

Eli Lilly Didn’t Buy Oura. It Bought Proximity.

Eli Lilly took an undisclosed equity stake in Oura, not a company. What that says about personalised medicine and the future of drug delivery.

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28 July 2026TechnologyBy George Forrest

The Colour of Taste

Why a red syrup tastes sweeter before it’s swallowed: the psychology of colour, taste and liquid medicine, from Ibumix.

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23 July 2026UncategorisedBy George Forrest

Shake Well Before Use

A Label That Quietly Admits Defeat A pharmacy refilled a child’s epilepsy suspension from a stock bottle that had not been shaken […]

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