The Molecule Must Earn the Patch
Five NSAIDs from one pharmacological class have five different transdermal fates. No molecular descriptor predicts which, and neither does the flux calculation that comes closest.
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Two Roads to One Pill
Ozempic is a pill now, but oral bioavailability wasn’t solved. How Novo Nordisk and Eli Lilly reached comparable results by two opposite routes.
Read moreThe Third Battle, Better on Paper
A 2020 mouse study hit an oral bioavailability no approved oral peptide drug has matched in a human. Why lipid-based delivery — […]
Read moreThe Second Battle, Opened From the Inside
The Second Battle, Opened From the Inside Octreotide, acromegaly and the tight-junction trick that takes on the gut wall directly Rybelsus proved […]
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